Compound Detail
CHEMBL197965
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Basic Information
| ChEMBL ID | CHEMBL197965 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FNTPFIQEKNCIBW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
511.1
MW (Da)
4.14
ALogP
7
HBA
3
HBD
119.9
PSA (Ų)
0.17
QED
1
Ro5 Violations
16
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 CHEMBL1875 | Ki | 7.89 | 7.89 | 13.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Ki | = | 13.0 | nM | 7.89 | Binding affinity for 5-HT4 receptor using [3H]GR-113808 | 16190749 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16190749 | 10.1021/jm050234z | 5-hydroxytryptamine receptor 4 | 2 |
Data from ChEMBL 36 via Core Engine