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Compound Detail

CHEMBL2006030

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CCN(/N=C/c1ccc(Cl)cc1)c1cc(=O)n(C)c(=O)[nH]1

Basic Information

ChEMBL ID CHEMBL2006030
Phase Preclinical
Structure Type MOL
InChI Key OSHPWVBGYYZDQD-CXUHLZMHSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

306.8
MW (Da)
1.59
ALogP
5
HBA
1
HBD
70.5
PSA (Ų)
0.69
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C14H15ClN4O2
MW 306.75
Aromatic Rings 2
Heavy Atoms 21
NP-Likeness -1.19

Activity Summary

EC50 2 meas. best 5.95

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Aryl hydrocarbon receptor
CHEMBL3201
EC50 5.95 5.95 1118.0 1
Nuclear receptor subfamily 1 group I member 2
CHEMBL3401
EC50 4.11 4.11 78478.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine