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Compound Detail

CHEMBL2021531

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CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@H](CC(=O)c1nc(C(=O)N[C@@H](Cc2ccccc2)C[C@H](C)C(=O)O)cs1)C(C)C.Cl

Basic Information

ChEMBL ID CHEMBL2021531
Phase Preclinical
Structure Type MOL
InChI Key JXJBTOJZDRYEAA-KMODKYMMSA-N
Parent Compound CHEMBL2027962
Active Moiety CHEMBL2027962
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

641.8
MW (Da)
3.59
ALogP
8
HBA
5
HBD
166.6
PSA (Ų)
0.16
QED
1
Ro5 Violations
17
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C33H48ClN5O6S
MW 678.30
Aromatic Rings 2
Heavy Atoms 45
NP-Likeness -0.07

Literature References

PubMed DOI Target Context # Activities
18314944 10.1021/jm701321p 1A9 1

Data from ChEMBL 36 via Core Engine