Compound Detail
CHEMBL2023268
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Basic Information
| ChEMBL ID | CHEMBL2023268 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZSHBGEUUYAVAIN-MDZDMXLPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
295.3
MW (Da)
3.93
ALogP
2
HBA
1
HBD
42.2
PSA (Ų)
0.74
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty acid-binding protein, adipocyte CHEMBL2021755 | Ki | 7.48 | 7.48 | 33.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty acid-binding protein, adipocyte | Ki | = | 33.0 | nM | 7.48 | Inhibition of rat ap2 by fluorescent 1,8-anilino-8-naphthalene sulfonate assay | 22483089 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22483089 | 10.1016/j.ejmech.2012.03.006 | Mus musculus | 9 |
| 22483089 | 10.1016/j.ejmech.2012.03.006 | RAW264.7 | 1 |
| 22483089 | 10.1016/j.ejmech.2012.03.006 | Fatty acid-binding protein, adipocyte | 1 |
Data from ChEMBL 36 via Core Engine