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Compound Detail

CHEMBL2035908

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CC1(C)CC[C@]23CC[C@]4(C)[C@H](CC[C@@H]5[C@@]6(C)CC(Br)C(=O)C(C)(C)[C@@H]6CC[C@]54C)[C@H]2[C@H]1OC3

Basic Information

ChEMBL ID CHEMBL2035908
Phase Preclinical
Structure Type MOL
InChI Key ZSYCMXVHYNLFBD-RGEODBJDSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

519.6
MW (Da)
7.82
ALogP
2
HBA
0
HBD
26.3
PSA (Ų)
0.31
QED
2
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C30H47BrO2
MW 519.61
Aromatic Rings 0
Heavy Atoms 33
NP-Likeness 3.02

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
24694263 10.1021/np400947d NON-PROTEIN TARGET 2
22551630 10.1016/j.bmc.2012.03.066 CCRF-CEM 1
24694263 10.1021/np400947d NCI-H460 1
24694263 10.1021/np400947d SF-268 1
24694263 10.1021/np400947d MCF7 1
24694263 10.1021/np400947d DU-145 1
27236068 10.1016/j.ejmech.2016.05.029 NON-PROTEIN TARGET 1

Data from ChEMBL 36 via Core Engine