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Compound Detail

CHEMBL2037034

BRUCEANIC ACID E METHYL ESTER
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COC(=O)C[C@]1(C)[C@H]2[C@@H](O)[C@H](O)[C@@]3(C(=O)OC)OC[C@@]24[C@@H](C[C@H]1C(C)=O)OC(=O)[C@H](OC(=O)C=C(C)C)[C@@H]34

Basic Information

ChEMBL ID CHEMBL2037034
Name BRUCEANIC ACID E METHYL ESTER
Phase Preclinical
Structure Type MOL
InChI Key RJGMSKOOJDAQCS-RQSDTPCRSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

538.5
MW (Da)
-0.14
ALogP
12
HBA
2
HBD
172.0
PSA (Ų)
0.26
QED
2
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C26H34O12
MW 538.55
Aromatic Rings 0
Heavy Atoms 38
NP-Likeness 3.22

Literature References

PubMed DOI Target Context # Activities
22506620 10.1021/np200920c HCT-8 1
22506620 10.1021/np200920c HepG2 1
22506620 10.1021/np200920c BGC-823 1
22506620 10.1021/np200920c A549 1
22506620 10.1021/np200920c SK-OV-3 1

Data from ChEMBL 36 via Core Engine