Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL207049

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
FC(F)(F)c1cccc(Nc2nnc(-c3cccnc3CCCc3ccc4c(c3)OCO4)o2)c1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL207049
Phase Preclinical
Structure Type MOL
InChI Key HFVSTLBPVWQSID-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

468.4
MW (Da)
5.80
ALogP
7
HBA
1
HBD
82.3
PSA (Ų)
0.37
QED
1
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C24H19F3N4O3
MW 468.44
Aromatic Rings 4
Heavy Atoms 34
NP-Likeness -1.09

Literature References

PubMed DOI Target Context # Activities
16460936 10.1016/j.bmcl.2005.12.090 Vascular endothelial growth factor receptor 2 2
16460936 10.1016/j.bmcl.2005.12.090 Vascular endothelial growth factor receptor 1 1
16460936 10.1016/j.bmcl.2005.12.090 Bcr/Abl fusion protein 1
16460936 10.1016/j.bmcl.2005.12.090 Cyclin-dependent kinase 2 1
16460936 10.1016/j.bmcl.2005.12.090 Cyclin-dependent kinase 5 1

Data from ChEMBL 36 via Core Engine