Compound Detail
CHEMBL2089252
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Basic Information
| ChEMBL ID | CHEMBL2089252 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZCRBGKLRDJDKNG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
282.4
MW (Da)
2.59
ALogP
5
HBA
2
HBD
84.0
PSA (Ų)
0.85
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Small ribosomal subunit protein eS27 CHEMBL1932893 | IC50 | 5.4 | 5.4 | 3970.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Small ribosomal subunit protein eS27 | IC50 | = | 3970.0 | nM | 5.4 | Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA ass... | 24900510 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24900510 | 10.1021/ml3000879 | Small ribosomal subunit protein eS27 | 1 |
| 24900510 | 10.1021/ml3000879 | Mitogen-activated protein kinase 8 | 1 |
Data from ChEMBL 36 via Core Engine