Compound Detail
CHEMBL209401
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Basic Information
| ChEMBL ID | CHEMBL209401 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MTZMMGKPBKFVFB-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
303.4
MW (Da)
3.15
ALogP
5
HBA
1
HBD
68.1
PSA (Ų)
0.87
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage migration inhibitory factor CHEMBL1926491 | IC50 | 5.6 | 5.6 | 2500.0 | 1 |
| Macrophage migration inhibitory factor CHEMBL2085 | IC50 | 5.6 | 5.6 | 2500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage migration inhibitory factor | IC50 | = | 2500.0 | nM | 5.6 | Inhibition of MIF tautomerase activity | 16682188 |
| Macrophage migration inhibitory factor | IC50 | = | 2500.0 | nM | 5.6 | Enzyme Assay: MIF tautomerase activity was measured by UV-Visible recording spec... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16682188 | 10.1016/j.bmcl.2006.04.038 | Macrophage migration inhibitory factor | 1 |
Data from ChEMBL 36 via Core Engine