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Compound Detail

CHEMBL2104970

INCYCLINIDE
🧪 Phase II
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🧪 Phase II
NC(=O)C1=C(O)C[C@@H]2C[C@@H]3Cc4cccc(O)c4C(=O)C3=C(O)[C@]2(O)C1=O

Basic Information

ChEMBL ID CHEMBL2104970
Name INCYCLINIDE
Phase Phase II
Structure Type MOL
InChI Key ZXFCRFYULUUSDW-OWXODZSWSA-N

Known Names

COL-3 Inciclinida Incyclinide Metastat NSC-683551
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
5
Known Names
2
Indications

Molecular Properties

371.4
MW (Da)
0.58
ALogP
7
HBA
5
HBD
158.2
PSA (Ų)
0.45
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Single Enantiomer

Flags

Natural Product
USAN Year 2005

Extended Properties

Molecular Formula C19H17NO7
MW 371.35
Aromatic Rings 1
Heavy Atoms 27
NP-Likeness 1.50

Indications

Central Nervous System Neoplasms Neoplasms

Activity Summary

IC50 2 meas.

Literature References

PubMed DOI Target Context # Activities
31098005 10.1021/acsmedchemlett.9b00091 Unchecked 3
31098005 10.1021/acsmedchemlett.9b00091 microRNA 21 3

Data from ChEMBL 36 via Core Engine