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Compound Detail

CHEMBL2106939

POLIHEXANIDE
💊 Approved Drug
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💊 Approved Drug
CCCCCCNC(=N)NC(=N)N
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL2106939
Name POLIHEXANIDE
Phase Approved
Structure Type MOL
InChI Key VAZJLPXFVQHDFB-UHFFFAOYSA-N
Therapeutic ✓ Yes

Known Names

Akantior Cosmocil cq Lavasept Microcare mbg Polihexanida Polihexanide Polihexanide hydrochloride Poly(hexamethylenebiguanide) Polyhexamethylene biguanide Purista Vantocil
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
11
Known Names
4
Indications
2
Mechanisms

Molecular Properties

185.3
MW (Da)
0.57
ALogP
2
HBA
5
HBD
97.8
PSA (Ų)
0.25
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
First Approval 2024
Availability Unknown
Chirality Achiral

Extended Properties

Molecular Formula C8H19N5
MW 185.27
Aromatic Rings 0
Heavy Atoms 13
NP-Likeness 0.21

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Cell membrane disrupting agent DISRUPTING AGENT Cell membrane ✓ ✓
Cell membrane disrupting agent DISRUPTING AGENT Cell membrane ✓ ✓

Indications

Acanthamoeba Keratitis Eye Infections Mycoses Pulpitis

ATC Classification

D08AC05
polihexanide
Level 1: DERMATOLOGICALS
Level 2: ANTISEPTICS AND DISINFECTANTS
S01AX24
polihexanide
Level 1: SENSORY ORGANS
Level 2: OPHTHALMOLOGICALS

Data from ChEMBL 36 via Core Engine