Compound Detail
CHEMBL2107135
TESIMIDE 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL2107135 |
| Name | TESIMIDE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | JFTOCKFCHJCDDX-UVTDQMKNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
3
Known Names
Molecular Properties
253.3
MW (Da)
2.60
ALogP
2
HBA
1
HBD
46.2
PSA (Ų)
0.62
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
EC50 1 meas. best 4.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| No relevant target CHEMBL2362975 | EC50 | 4.58 | 4.58 | 26000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| No relevant target | EC50 | = | 26000.0 | nM | 4.58 | Induction of ROS generation assessed as generation of H2O2 measured as oxidation... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C3MD00149K | NON-PROTEIN TARGET | 4 |
| - | 10.1039/C3MD00149K | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine