Compound Detail
CHEMBL214229
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL214229 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MBWYPZWHIVSGJT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
384.5
MW (Da)
1.79
ALogP
6
HBA
1
HBD
76.5
PSA (Ų)
0.85
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 2 CHEMBL5373 | Ki | 7.17 | 7.17 | 67.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 2 | Ki | = | 67.2 | nM | 7.17 | Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen | 17004710 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17004710 | 10.1021/jm0603466 | Cannabinoid receptor 1 | 1 |
| 17004710 | 10.1021/jm0603466 | Cannabinoid receptor 2 | 1 |
| 17004710 | 10.1021/jm0603466 | Cannabinoid receptor | 1 |
Data from ChEMBL 36 via Core Engine