Compound Detail
CHEMBL2158033
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Basic Information
| ChEMBL ID | CHEMBL2158033 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XILUNHGLVJVDGW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
476.6
MW (Da)
3.90
ALogP
6
HBA
1
HBD
77.1
PSA (Ų)
0.53
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | Ki | 7.57 | 7.57 | 27.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | Ki | = | 27.0 | nM | 7.57 | Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells a... | 22926225 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22926225 | 10.1016/j.ejmech.2012.07.043 | 5-hydroxytryptamine receptor 7 | 1 |
Data from ChEMBL 36 via Core Engine