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Compound Detail

CHEMBL2164448

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Cc1ccc(S(=O)(=O)N[C@@H]2CCN(c3nc(NCc4ccccc4)nc(N[C@H]4CCCCNC4=O)n3)C2)cc1F

Basic Information

ChEMBL ID CHEMBL2164448
Phase Preclinical
Structure Type MOL
InChI Key BTJVBMZQYZDSSY-OFNKIYASSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

568.7
MW (Da)
2.57
ALogP
9
HBA
4
HBD
141.2
PSA (Ų)
0.31
QED
1
Ro5 Violations
9
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H33FN8O3S
MW 568.68
Aromatic Rings 3
Heavy Atoms 40
NP-Likeness -1.68

Literature References

PubMed DOI Target Context # Activities
22891645 10.1021/jm300449x A disintegrin and metalloproteinase with thrombospondin motifs 5 1

Data from ChEMBL 36 via Core Engine