Compound Detail
CHEMBL216478
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Basic Information
| ChEMBL ID | CHEMBL216478 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OPXKCSMQHPTQDF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
315.4
MW (Da)
4.54
ALogP
4
HBA
1
HBD
74.2
PSA (Ų)
0.84
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor 4 CHEMBL3190 | EC50 | 5.7 | 5.7 | 1979.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor 4 | EC50 | = | 1979.0 | nM | 5.7 | Activity against human GLUR4 flip expressed in HEK293 cells assessed as glutamat... | 16879964 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16879964 | 10.1016/j.bmcl.2006.07.035 | Glutamate receptor 4 | 2 |
| 16879964 | 10.1016/j.bmcl.2006.07.035 | Glutamate receptor 2 | 2 |
Data from ChEMBL 36 via Core Engine