Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL2169983

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cccc(OC(F)(F)F)c1)CC2
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL2169983
Phase Preclinical
Structure Type MOL
InChI Key FTGGMBBDQLBTAQ-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

420.3
MW (Da)
5.21
ALogP
3
HBA
1
HBD
50.8
PSA (Ų)
0.69
QED
1
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H14F6N2O3
MW 420.31
Aromatic Rings 2
Heavy Atoms 29
NP-Likeness -1.43

Literature References

PubMed DOI Target Context # Activities
24900481 10.1021/ml300008j Plasmodium falciparum 3
24900481 10.1021/ml300008j Unchecked 1
24900481 10.1021/ml300008j 5-hydroxytryptamine receptor 2C 1

Data from ChEMBL 36 via Core Engine