Compound Detail
CHEMBL2171880
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)O
Basic Information
| ChEMBL ID | CHEMBL2171880 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | BVRWWHKWGPOKPN-NXOPMQQOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1191.4
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Kallikrein-2 CHEMBL2442 | Ki | 5.85 | 5.85 | 1410.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Kallikrein-2 | Ki | = | 1410.0 | nM | 5.85 | Inhibition of human KLK2 after 1 hr by phage-display based Immunofluorometric As... | 22607152 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22607152 | 10.1021/jm300407t | Kallikrein-2 | 1 |
Data from ChEMBL 36 via Core Engine