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Compound Detail

CHEMBL217370

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CCCc1cc(=O)n([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]3OP(=O)(O)O[C@H]32)c(=O)[nH]1

Basic Information

ChEMBL ID CHEMBL217370
Phase Preclinical
Structure Type MOL
InChI Key TVHZXCKQSILXQE-QCNRFFRDSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

588.2
MW (Da)
-0.39
ALogP
13
HBA
6
HBD
279.7
PSA (Ų)
0.19
QED
3
Ro5 Violations
10
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C12H20N2O17P4
MW 588.19
Aromatic Rings 1
Heavy Atoms 35
NP-Likeness 0.91

Literature References

PubMed DOI Target Context # Activities
17125260 10.1021/jm060848j P2Y purinoceptor 2 3
17125260 10.1021/jm060848j P2Y purinoceptor 6 2
17125260 10.1021/jm060848j P2Y purinoceptor 4 2

Data from ChEMBL 36 via Core Engine