Compound Detail
CHEMBL218643
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Basic Information
| ChEMBL ID | CHEMBL218643 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HVLBCVJJDOICDV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
272.4
MW (Da)
1.65
ALogP
2
HBA
2
HBD
58.2
PSA (Ų)
0.80
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 1 CHEMBL3571 | Ki | 5.18 | 5.18 | 6670.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 | Ki | = | 6670.0 | nM | 5.18 | Displacement of [3H]SR141716A from CB1 receptor in rat cerebellar membrane after... | 19762126 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19762126 | 10.1016/j.ejmech.2009.08.003 | Cannabinoid receptor 1 | 3 |
| 17228882 | 10.1021/jm0601102 | Peroxisome proliferator-activated receptor alpha | 2 |
| 19762126 | 10.1016/j.ejmech.2009.08.003 | Cannabinoid receptor 2 | 2 |
| 17228882 | 10.1021/jm0601102 | Rattus norvegicus | 1 |
| 19762126 | 10.1016/j.ejmech.2009.08.003 | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine