Compound Detail
CHEMBL219065
NOBILIN D Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL219065 |
| Name | NOBILIN D |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SCNNIVKGPABBOM-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
320.3
MW (Da)
2.40
ALogP
6
HBA
3
HBD
88.4
PSA (Ų)
0.76
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW CHEMBL614631 | IC50 | 4.82 | 4.82 | 15300.0 | 1 |
| No relevant target CHEMBL2362975 | IC50 | 4.7 | 4.7 | 19900.0 | 1 |
| Radical scavenging activity CHEMBL613712 | IC50 | 4.7 | 4.7 | 19900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW | IC50 | = | 15300.0 | nM | 4.82 | Inhibition of LPS and TNF-alpha-activated NO production in murine RAW 264.7 cell... | 17253844 |
| Radical scavenging activity | IC50 | = | 19900.0 | nM | 4.7 | Antioxidant activity assessed by DPPH radical scavenging assay | 17253844 |
| No relevant target | IC50 | = | 19900.0 | nM | 4.7 | Antioxidant activity assessed as DPPH radical scavenging activity incubated for ... | 32711292 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17253844 | 10.1021/np060449r | Radical scavenging activity | 1 |
| 17253844 | 10.1021/np060449r | NON-PROTEIN TARGET | 1 |
| 17253844 | 10.1021/np060449r | RAW | 1 |
| 32711292 | 10.1016/j.ejmech.2020.112530 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine