Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL219290

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COc1ccc(F)cc1C(C)(C)CC(O)(Cn1ccc(=O)cc1)C(F)(F)F
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL219290
Phase Preclinical
Structure Type MOL
InChI Key GRBCNFHNMVJUEQ-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

387.4
MW (Da)
3.66
ALogP
4
HBA
1
HBD
51.5
PSA (Ų)
0.77
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H21F4NO3
MW 387.37
Aromatic Rings 2
Heavy Atoms 27
NP-Likeness -0.56

Literature References

PubMed DOI Target Context # Activities
17181172 10.1021/jm061273t Glucocorticoid receptor 1
17181172 10.1021/jm061273t Progesterone receptor 1
17181172 10.1021/jm061273t HFF 1
17181172 10.1021/jm061273t Mineralocorticoid receptor 1

Data from ChEMBL 36 via Core Engine