Compound Detail
CHEMBL2206306
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CCCCCCCN(CCc1ccc(O[C@@H](Cc2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1.NC1CCCCC1
Basic Information
| ChEMBL ID | CHEMBL2206306 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KQVYIGLKGUWHDO-JMAPEOGHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
599.8
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma CHEMBL235 | EC50 | 5.77 | 5.77 | 1700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma | EC50 | = | 1700.0 | nM | 5.77 | Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed i... | 22081932 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22081932 | 10.1021/jm201306q | Peroxisome proliferator-activated receptor gamma | 3 |
| 22081932 | 10.1021/jm201306q | Peroxisome proliferator-activated receptor delta | 2 |
| 22081932 | 10.1021/jm201306q | Peroxisome proliferator-activated receptor alpha | 2 |
| 22081932 | 10.1021/jm201306q | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine