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Compound Detail

CHEMBL2207072

SODIUM ISOTHIOCYANATE
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[N-]=C=S.[Na+]

Basic Information

ChEMBL ID CHEMBL2207072
Name SODIUM ISOTHIOCYANATE
Phase Preclinical
Structure Type MOL
InChI Key RROSXLCQOOGZBR-UHFFFAOYSA-N
Parent Compound CHEMBL1161685
Active Moiety CHEMBL1161685
1
Targets
21
Activities
1
Assay Types
0
PK Parameters
17
Publications
0
Known Names

Molecular Properties

59.1
MW (Da)
0.67
ALogP
2
HBA
1
HBD
23.9
PSA (Ų)
0.32
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula CNNaS
MW 81.08
Aromatic Rings 0
Heavy Atoms 3
NP-Likeness -0.10

Activity Summary

Ki 21 meas. best 4.03

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 4.03 4.03 93000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked Ki = 93000.0 nM 4.03 Inhibition of Porphyromonas gingivalis recombinant CA by CO2 hydration assay 23769640

Literature References

Data from ChEMBL 36 via Core Engine