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Compound Detail

CHEMBL2208204

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CO[C@H]1C=C[C@@]23c4cc5c(cc4CN(C)[C@@H]2C(=O)N(C)[C@H]3C1)OCO5

Basic Information

ChEMBL ID CHEMBL2208204
Phase Preclinical
Structure Type MOL
InChI Key VGYPIERRFRENJI-CTSOBWNQSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

342.4
MW (Da)
1.28
ALogP
5
HBA
0
HBD
51.2
PSA (Ų)
0.72
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C19H22N2O4
MW 342.40
Aromatic Rings 1
Heavy Atoms 25
NP-Likeness 2.15

Literature References

PubMed DOI Target Context # Activities
23190013 10.1021/np3005425 HT-29 1
23190013 10.1021/np3005425 HepG2 1
23190013 10.1021/np3005425 A549 1
23190013 10.1021/np3005425 K562 1
23190013 10.1021/np3005425 HL-60 1

Data from ChEMBL 36 via Core Engine