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Compound Detail

CHEMBL2219411

MOMELOTINIB DIHYDROCHLORIDE
💊 Approved Drug
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💊 Approved Drug
Cl.Cl.N#CCNC(=O)c1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL2219411
Name MOMELOTINIB DIHYDROCHLORIDE
Phase Approved
Structure Type MOL
InChI Key IPNATXQRPWRHKD-UHFFFAOYSA-N
Therapeutic ✓ Yes
Parent Compound CHEMBL1078178
Active Moiety CHEMBL1078178

Known Names

CYT-387 DIHYDROCHLORIDE CYT387 CYT387 DIHYDROCHLORIDE Momelotinib dihydrochloride Ojjaara
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
5
Known Names
3
Indications

Molecular Properties

414.5
MW (Da)
2.98
ALogP
7
HBA
2
HBD
103.2
PSA (Ų)
0.60
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
First Approval 2023
Availability Prescription
Chirality Achiral

Routes of Administration

Oral
USAN Stem -tinib
USAN Year 2012

Extended Properties

Molecular Formula C23H24Cl2N6O2
MW 487.39
Aromatic Rings 3
Heavy Atoms 31
NP-Likeness -1.88

Indications

Polycythemia Vera Primary Myelofibrosis Thrombocythemia, Essential

Data from ChEMBL 36 via Core Engine