Compound Detail
CHEMBL2228308
POTASSIUM CYANIDE Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2228308 |
| Name | POTASSIUM CYANIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NNFCIKHAZHQZJG-UHFFFAOYSA-N |
| Parent Compound | CHEMBL183419 |
| Active Moiety | CHEMBL183419 |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
27.0
MW (Da)
0.14
ALogP
1
HBA
0
HBD
23.8
PSA (Ų)
0.37
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL3318 | IC50 | 4.62 | 4.62 | 24000.0 | 1 |
| Aldehyde oxidase 1 CHEMBL1641356 | IC50 | 4.16 | 4.16 | 69000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | IC50 | = | 24000.0 | nM | 4.62 | Inhibition of Agaricus bisporus (mushroom) tyrosinase | 21476569 |
| Aldehyde oxidase 1 | IC50 | = | 69000.0 | nM | 4.16 | Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosol | 21476569 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19685448 | 10.1002/ps.1820 | Botrytis cinerea | 4 |
| 21476569 | 10.1021/jf200485k | Unchecked | 2 |
| 21476569 | 10.1021/jf200485k | Aldehyde oxidase 1 | 1 |
| 21476569 | 10.1021/jf200485k | Tyrosinase | 1 |
| - | 10.1039/C0MD00135J | Homo sapiens | 1 |
| 26571192 | 10.1021/acs.jmedchem.5b01013 | Mus musculus | 1 |
| 33253573 | 10.1021/acs.jnatprod.0c00651 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine