Compound Detail
CHEMBL2230077
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Basic Information
| ChEMBL ID | CHEMBL2230077 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FEXDVTRZRUHVJU-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
243.7
MW (Da)
2.37
ALogP
4
HBA
0
HBD
66.1
PSA (Ų)
0.59
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 9.49
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 9.49 | 8.38 | 0.3 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 0.32 | nM | 9.49 | Displacement of [3H]-methyl-SFX from nAChR in Myzus persicae 4106A (green peach ... | 23112103 |
| Unchecked | Ki | = | 54.0 | nM | 7.27 | Displacement of [3H]IMD from nAChR in Myzus persicae 4106A (green peach aphid) m... | 23112103 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21105655 | 10.1021/jf102765x | Bemisia tabaci | 4 |
| 21105655 | 10.1021/jf102765x | Myzus persicae | 4 |
| 23112103 | 10.1002/ps.3413 | Unchecked | 2 |
| 21105655 | 10.1021/jf102765x | Latrodectus hesperus | 1 |
| 21105655 | 10.1021/jf102765x | Aphis gossypii | 1 |
| 23112103 | 10.1002/ps.3413 | Myzus persicae | 1 |
Data from ChEMBL 36 via Core Engine