Compound Detail
CHEMBL2236843
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Basic Information
| ChEMBL ID | CHEMBL2236843 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MLDPSXZLBYAKAZ-GQCTYLIASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
304.3
MW (Da)
3.88
ALogP
3
HBA
0
HBD
35.5
PSA (Ų)
0.62
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| SGC-7901 CHEMBL614909 | IC50 | 4.25 | 4.25 | 55540.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| SGC-7901 | IC50 | = | 55540.0 | nM | 4.25 | Cytotoxicity against Homo sapiens (human) SGC7901 cells after 72 hr by MTT assay | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-011-9549-9 | HT-29 | 1 |
| - | 10.1007/s00044-011-9549-9 | SGC-7901 | 1 |
Data from ChEMBL 36 via Core Engine