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Compound Detail

CHEMBL2270709

6-F-D-DIBOA
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O=C1COc2ccc(F)cc2N1O

Basic Information

ChEMBL ID CHEMBL2270709
Name 6-F-D-DIBOA
Phase Preclinical
Structure Type MOL
InChI Key LGSRGAGHVDOILK-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

183.1
MW (Da)
0.94
ALogP
3
HBA
1
HBD
49.8
PSA (Ų)
0.61
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C8H6FNO3
MW 183.14
Aromatic Rings 1
Heavy Atoms 13
NP-Likeness -0.94

Activity Summary

IC50 2 meas. best 5.55

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Echinochloa crus-galli
CHEMBL612343
IC50 5.55 5.55 2800.0 1
Oryza sativa
CHEMBL613061
IC50 5.05 5.05 9000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
19551813 10.1002/ps.1799 Unchecked 1
19551813 10.1002/ps.1799 Oryza sativa 1
19551813 10.1002/ps.1799 Echinochloa crus-galli 1

Data from ChEMBL 36 via Core Engine