Compound Detail
CHEMBL227929
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Basic Information
| ChEMBL ID | CHEMBL227929 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZFGGWTSPWIUVKH-UVTDQMKNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
313.4
MW (Da)
3.80
ALogP
4
HBA
1
HBD
40.5
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.07 | 5.07 | 8590.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 8590.14 | nM | 5.07 | Inhibition of Plasmodium falciparum enoyl-ACP reductase expressed in Escherichia... | 23499236 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17477517 | 10.1021/jm061257w | Enoyl-acyl-carrier protein reductase | 3 |
| 23499236 | 10.1016/j.bmcl.2013.02.006 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine