Compound Detail
CHEMBL2286828
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2286828 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZYNSABAKIVOKFP-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
346.8
MW (Da)
4.58
ALogP
4
HBA
1
HBD
60.5
PSA (Ų)
0.83
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.88
IC50 1 meas. best 6.49
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cytochrome b-c1 complex subunit Rieske, mitochondrial CHEMBL2366433 | IC50 | 6.49 | 6.49 | 323.6 | 1 |
| Rhizoctonia solani CHEMBL613272 | EC50 | 4.88 | 4.88 | 13182.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cytochrome b-c1 complex subunit Rieske, mitochondrial | IC50 | = | 323.59 | nM | 6.49 | Inhibition of Botryotinia fuckeliana succinate dehydrogenase by DCPIP-based spec... | - |
| Rhizoctonia solani | EC50 | = | 13182.57 | nM | 4.88 | Antifungal activity against Rhizoctonia solani infested in rice seedling incubat... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1584/jpestics.17.2_91 | Cytochrome b-c1 complex subunit Rieske, mitochondrial | 1 |
| - | 10.1584/jpestics.17.2_91 | Rhizoctonia solani | 1 |
| - | 10.1584/jpestics.17.2_91 | Botrytis cinerea | 1 |
Data from ChEMBL 36 via Core Engine