Compound Detail
CHEMBL232103
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL232103 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PIFUTIDFOAPUKO-DCAQKATOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
264.3
MW (Da)
-0.43
ALogP
4
HBA
1
HBD
76.4
PSA (Ų)
0.73
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 8.74 | 8.74 | 1.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 | IC50 | = | 1.8 | nM | 8.74 | Inhibition of human DPP4 | 17293118 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17293118 | 10.1016/j.bmc.2007.01.041 | Dipeptidyl peptidase 4 | 4 |
| 17293118 | 10.1016/j.bmc.2007.01.041 | Canis familiaris | 1 |
| 17293118 | 10.1016/j.bmc.2007.01.041 | Cynomolgus monkey | 1 |
| 17293118 | 10.1016/j.bmc.2007.01.041 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine