Compound Detail
CHEMBL2321890
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Basic Information
| ChEMBL ID | CHEMBL2321890 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CPOLUOFGIGGXAO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
284.2
MW (Da)
2.75
ALogP
3
HBA
0
HBD
41.9
PSA (Ų)
0.73
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Telomerase reverse transcriptase CHEMBL2916 | IC50 | 5.5 | 5.5 | 3140.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Telomerase reverse transcriptase | IC50 | = | 3140.0 | nM | 5.5 | Inhibition of telomerase-mediated supercoiling activity in human MGC803 cells af... | 23265905 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23265905 | 10.1016/j.bmcl.2012.11.101 | Molecular identity unknown | 1 |
| 23265905 | 10.1016/j.bmcl.2012.11.101 | Telomerase reverse transcriptase | 1 |
Data from ChEMBL 36 via Core Engine