Compound Detail
CHEMBL2331792
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Basic Information
| ChEMBL ID | CHEMBL2331792 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XOQMGSWBFVDATG-UHFFFAOYSA-N |
1
Targets
6
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
168.2
MW (Da)
0.37
ALogP
4
HBA
1
HBD
47.3
PSA (Ų)
0.66
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas.
EC50 2 meas. best 4.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2C CHEMBL225 | EC50 | 4.92 | 4.92 | 12000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2C | EC50 | = | 12022.64 | nM | 4.92 | Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as i... | 23301527 |
| 5-hydroxytryptamine receptor 2C | EC50 | = | 12000.0 | nM | 4.92 | Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as i... | 23301527 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23301527 | 10.1021/jm301656h | 5-hydroxytryptamine receptor 2C | 5 |
| 23301527 | 10.1021/jm301656h | 5-hydroxytryptamine receptor 2A | 3 |
Data from ChEMBL 36 via Core Engine