Compound Detail
CHEMBL2333594
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Basic Information
| ChEMBL ID | CHEMBL2333594 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DSQCUCZJPJZOOD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
379.5
MW (Da)
3.23
ALogP
6
HBA
1
HBD
77.1
PSA (Ų)
0.52
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ephrin type-B receptor 4 CHEMBL5147 | IC50 | 5.89 | 5.89 | 1300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ephrin type-B receptor 4 | IC50 | = | 1300.0 | nM | 5.89 | Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-... | 23253074 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23253074 | 10.1021/jm301187e | Ephrin type-B receptor 4 | 3 |
Data from ChEMBL 36 via Core Engine