Compound Detail
CHEMBL2336738
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Basic Information
| ChEMBL ID | CHEMBL2336738 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GKHCBYYBLTXYEV-UJPOAAIJSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
270.3
MW (Da)
-1.00
ALogP
6
HBA
4
HBD
99.4
PSA (Ų)
0.56
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HEK-293T CHEMBL3706568 | IC50 | 4.09 | 4.09 | 80300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HEK-293T | IC50 | = | 80300.0 | nM | 4.09 | Cytoprotective activity against CdCl2-induced cell death in human HEK293T cells ... | 31593459 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25127165 | 10.1016/j.bmcl.2014.07.057 | No relevant target | 5 |
| 25497988 | 10.1016/j.bmcl.2014.11.054 | RAW264.7 | 4 |
| 31593459 | 10.1021/acs.jnatprod.9b00212 | HEK-293T | 2 |
| 23356964 | 10.1021/np300609u | Radical scavenging activity | 1 |
| 25127165 | 10.1016/j.bmcl.2014.07.057 | Lysosomal alpha-glucosidase | 1 |
| 32991171 | 10.1021/acs.jnatprod.0c00756 | HT-22 | 1 |
Data from ChEMBL 36 via Core Engine