Compound Detail
CHEMBL2347288
2-METHYLADENOSINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2347288 |
| Name | 2-METHYLADENOSINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IQZWKGWOBPJWMX-IOSLPCCCSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
281.3
MW (Da)
-1.67
ALogP
9
HBA
4
HBD
139.5
PSA (Ų)
0.51
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.22 | 5.16 | 6000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 6000.0 | nM | 5.22 | Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate... | 7932587 |
| Unchecked | IC50 | = | 8000.0 | nM | 5.1 | Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate... | 7932587 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7932587 | 10.1021/jm00047a017 | Unchecked | 2 |
| 23434367 | 10.1016/j.bmc.2013.01.054 | Mycobacterium tuberculosis | 2 |
| 7932587 | 10.1021/jm00047a017 | Glyceraldehyde-3-phosphate dehydrogenase | 1 |
| 15801862 | 10.1021/jm0408924 | Mycobacterium tuberculosis | 1 |
| 23434367 | 10.1016/j.bmc.2013.01.054 | Unchecked | 1 |
| 23434367 | 10.1016/j.bmc.2013.01.054 | Vero | 1 |
Data from ChEMBL 36 via Core Engine