Compound Detail
CHEMBL2348289
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Basic Information
| ChEMBL ID | CHEMBL2348289 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QKYPMVYNTMNELG-AWEZNQCLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
623.2
MW (Da)
3.31
ALogP
5
HBA
3
HBD
97.0
PSA (Ų)
0.43
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proliferating cell nuclear antigen CHEMBL2346488 | IC50 | 5.85 | 5.85 | 1400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proliferating cell nuclear antigen | IC50 | = | 1400.0 | nM | 5.85 | Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carbox... | 23395113 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23395113 | 10.1016/j.bmc.2013.01.022 | Proliferating cell nuclear antigen | 5 |
| 23395113 | 10.1016/j.bmc.2013.01.022 | HeLa | 1 |
Data from ChEMBL 36 via Core Engine