Compound Detail
CHEMBL2368787
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Basic Information
| ChEMBL ID | CHEMBL2368787 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BQHXLVRLDGOOJK-USZNOCQGSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
266.3
MW (Da)
-1.37
ALogP
6
HBA
5
HBD
105.3
PSA (Ų)
0.46
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 6.26 | 6.26 | 550.0 | 1 |
| Lysosomal alpha-glucosidase CHEMBL2608 | Ki | 5.3 | 5.3 | 5000.0 | 1 |
| Beta-mannosidase CHEMBL3431 | Ki | 5.22 | 5.22 | 6000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 550.0 | nM | 6.26 | Inhibition against Alpha-maninosidase in jack bean | - |
| Lysosomal alpha-glucosidase | Ki | = | 5000.0 | nM | 5.3 | Inhibition against beta-glucosidase in sweet almond | - |
| Beta-mannosidase | Ki | = | 6000.0 | nM | 5.22 | Inhibition against Beta-mannosidase in snail | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00474-8 | Unchecked | 1 |
| - | 10.1016/0960-894X(95)00474-8 | Beta-mannosidase | 1 |
| - | 10.1016/0960-894X(95)00474-8 | Lysosomal alpha-glucosidase | 1 |
| - | 10.1016/0960-894X(95)00474-8 | Beta-galactosidase | 1 |
| - | 10.1016/0960-894X(95)00474-8 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine