Compound Detail
CHEMBL2370378
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CCOc1ccc(C[C@@H](NC(=O)CC23CC4CC(CC(C4)C2)C3)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCN)C(=O)N2CCC[C@@H]2C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)C(C)C)cc1
Basic Information
| ChEMBL ID | CHEMBL2370378 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AIJYNYNWKGUNQE-FPBZKOLWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
1268.6
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 7.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vasopressin V1 receptor CHEMBL2095221 | Kd | 7.64 | 7.64 | 22.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vasopressin V1 receptor | Kd | = | 22.91 | nM | 7.64 | pA2 value was determined for Vasopressin V1 receptor antagonistic activity in vi... | 2231609 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2231609 | 10.1021/jm00173a027 | Vasopressin V1 receptor | 2 |
| 2231609 | 10.1021/jm00173a027 | Vasopressin V2 receptor | 2 |
| 2231609 | 10.1021/jm00173a027 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine