Compound Detail
CHEMBL2376291
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Basic Information
| ChEMBL ID | CHEMBL2376291 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CCYYRIRDVPAGJO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
398.5
MW (Da)
2.57
ALogP
6
HBA
1
HBD
71.8
PSA (Ų)
0.66
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.6 | 5.6 | 2500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2500.0 | nM | 5.6 | Inhibition of caspase-like activity of 20S proteasome in rabbit erythrocytes usi... | 23541650 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23541650 | 10.1016/j.bmcl.2013.02.079 | Unchecked | 3 |
| 23541650 | 10.1016/j.bmcl.2013.02.079 | Cathepsin B | 1 |
Data from ChEMBL 36 via Core Engine