Compound Detail
CHEMBL2380802
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Basic Information
| ChEMBL ID | CHEMBL2380802 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LZNSXAAOXCUXIS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
288.3
MW (Da)
2.16
ALogP
5
HBA
0
HBD
45.4
PSA (Ų)
0.85
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 CHEMBL2492 | Ki | 7.94 | 7.94 | 11.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 | Ki | = | 11.6 | nM | 7.94 | Binding affinity to alpha7 nAChR (unknown origin) | 23507153 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23507153 | 10.1016/j.bmc.2013.02.018 | Neuronal acetylcholine receptor subunit alpha-7 | 1 |
Data from ChEMBL 36 via Core Engine