Compound Detail
CHEMBL2385097
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Basic Information
| ChEMBL ID | CHEMBL2385097 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LWNUJYSZDAFRCB-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
334.1
MW (Da)
3.80
ALogP
2
HBA
2
HBD
53.1
PSA (Ų)
0.71
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.96 | 5.96 | 1100.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1100.0 | nM | 5.96 | Inhibition of H1N1 Influenza A endonuclease after 1 hr by fluorescence assay | 24936242 |
| Unchecked | IC50 | = | 1100.0 | nM | 5.96 | Endonuclease Assay: The PAN domain has been shown to cleave ssRNA as well as ssD... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24936242 | 10.1021/ml4001112 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine