Compound Detail
CHEMBL238640
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL238640 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FPLPBYRFXXEWSG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
423.3
MW (Da)
3.32
ALogP
4
HBA
3
HBD
102.2
PSA (Ų)
0.17
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| ATP-sensitive inward rectifier potassium channel 11 CHEMBL1886 | EC50 | 5.37 | 5.37 | 4265.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| ATP-sensitive inward rectifier potassium channel 11 | EC50 | = | 4265.8 | nM | 5.37 | Channel opening activity at human bladder Kir6.2 channel containing SUR2B expres... | 17973362 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17973362 | 10.1021/jm7010194 | ATP-sensitive inward rectifier potassium channel 11 | 1 |
Data from ChEMBL 36 via Core Engine