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Compound Detail

CHEMBL2401865

OXYNTOMODULIN
Phase I
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Phase I
CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)O

Basic Information

ChEMBL ID CHEMBL2401865
Name OXYNTOMODULIN
Phase Phase I
Structure Type BOTH
InChI Key PXZWGQLGAKCNKD-DPNMSELWSA-N

Known Names

Oxyntomodulin
0
Targets
0
Activities
0
Assay Types
1
PK Parameters
4
Publications
1
Known Names
2
Indications

Molecular Properties

4421.9
MW (Da)

Drug Information

Molecule Type Protein
Chirality Single Enantiomer

Extended Properties

Molecular Formula C192H295N59O60S
MW 4421.89

Indications

Diabetes Mellitus, Type 2 Obesity

Pharmacokinetic Data

Parameter Value Units Species
T1/2 0.2 hr Homo sapiens

Literature References

PubMed DOI Target Context # Activities
23743288 10.1016/j.bmcl.2013.05.022 Homo sapiens 1
24044354 10.1021/jm400423p Glucagon receptor 1
24044354 10.1021/jm400423p Glucagon-like peptide 1 receptor 1
24044354 10.1021/jm400423p Dipeptidyl peptidase 4 1

Data from ChEMBL 36 via Core Engine