Compound Detail
CHEMBL241280
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Basic Information
| ChEMBL ID | CHEMBL241280 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NDFDVDHMWQFTIH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
296.4
MW (Da)
3.44
ALogP
2
HBA
3
HBD
48.0
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.34
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | Ki | 7.34 | 7.34 | 46.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | Ki | = | 46.0 | nM | 7.34 | Displacement of [3H]5CT from 5HT7 receptor expressed in HEK293 cells | 17317171 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17317171 | 10.1016/j.bmcl.2007.01.093 | 5-hydroxytryptamine receptor 7 | 1 |
| 17317171 | 10.1016/j.bmcl.2007.01.093 | Muscarinic acetylcholine receptor M4 | 1 |
| 17317171 | 10.1016/j.bmcl.2007.01.093 | D(2) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine