Compound Detail
CHEMBL241891
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL241891 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JYJSGIGNRCHKNP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
461.6
MW (Da)
5.54
ALogP
6
HBA
1
HBD
90.1
PSA (Ų)
0.26
QED
1
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cytosolic phospholipase A2 CHEMBL3816 | IC50 | 5.46 | 5.46 | 3500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cytosolic phospholipase A2 | IC50 | = | 3500.0 | nM | 5.46 | Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by... | 17320401 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17320401 | 10.1016/j.bmc.2007.02.016 | Cytosolic phospholipase A2 | 1 |
Data from ChEMBL 36 via Core Engine