Compound Detail
CHEMBL2424672
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2424672 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UEUAULUPWUEHIO-LLVKDONJSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
276.3
MW (Da)
-0.50
ALogP
6
HBA
1
HBD
73.3
PSA (Ų)
0.74
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 6.7 | 6.7 | 198.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 | IC50 | = | 198.0 | nM | 6.7 | Inhibition of human DPP-4 using Gly-pro-AMC as substrate preincubated for 10 min... | 23994324 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23994324 | 10.1016/j.ejmech.2013.08.010 | Dipeptidyl peptidase 4 | 1 |
Data from ChEMBL 36 via Core Engine