Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL2432028

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=c1[nH]cnc2sccc12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL2432028
Phase Preclinical
Structure Type MOL
InChI Key JEDVKUHCDPPWNR-UHFFFAOYSA-N
0
Targets
4
Activities
2
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

152.2
MW (Da)
0.98
ALogP
3
HBA
1
HBD
45.8
PSA (Ų)
0.61
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C6H4N2OS
MW 152.18
Aromatic Rings 2
Heavy Atoms 10
NP-Likeness -2.06

Activity Summary

IC50 3 meas.
Kd 1 meas.

Literature References

PubMed DOI Target Context # Activities
29541367 10.1021/acsmedchemlett.7b00512 Ubiquitin carboxyl-terminal hydrolase 7 4
23981144 10.1021/jm400718n Unchecked 3
24074844 10.1016/j.bmcl.2013.09.007 Poly [ADP-ribose] polymerase 1 2
29541367 10.1021/acsmedchemlett.7b00512 No relevant target 1

Data from ChEMBL 36 via Core Engine